Novartis revives an Indian experiment in China 

 

By R.N.Bhaskar


December 23, 2006 (published in the DNA). Please click here for the web version 2006_12_DNA_Novartis_revives_Indian_experiment_in_China_540kb.pdf


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Could it be a “do-unto-China-what-was-once-done-to-India”?

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<>In the first week of November, 2006, most observers of the pharmaceutical sector were pleasantly surprised at an announcement by Novartis, the fourth-largest pharmaceutical company in the world:  that it would be investing around US$100 million in China. Surprisingly, this investment would not be for selling drugs and medical products – it is what most pharmaceutical companies do – but to set up a new research facility in Shanghai. 

Prima facie, it does not make sense.  Why should any pharmaceutical company set up a research unit in a country where the legal underpinnings for protecting Intellectual Property Rights (IPRs) are weak?  Wasn’t that the reason why Cisco had a spat with Chinese companies?  And there are several articles on how China does not respect the IPR regime promoted by most developed countries in the world.

<>After all, pharmaceutical companies work with molecules that could lead to a cure of some ailment or the other.  They are extremely possessive about their IPRs and believe that this is the only way they can recover huge amounts of money that they invest in research and development.  So why should Novartis be keen on investing huge amounts of money in China which almost everyone acknowledges to be weak on the IPR front?

According to Novartis, it hopes that its new facility in Shanghai will eventually become one of its three big research hubs, alongside Cambridge, Massachusetts, and Basel (Switzerland) — and ahead of its other facilities in Vienna, London, La Jolla, New Jersey, Tokyo and Singapore.    Adds, John Gilardi, Head Corporate Public Relations, Novartis International AG, in an email communication to this columnist, “the new Shanghai R&D site will focus on finding new medicines to help patients in Asia with diseases common to the region, hence the initial focus on liver cancer caused by hepatitis. This is a unique project in that the site will be led by Chinese scientists working for people of China and this region.”

But there are sceptics who scoff at such claims.  They find Novartis’ moves a mere echo of those made by its erstwhile predecessor, Ciba-Geigy.  It may be recalled that Novartis is the new entity that was the result of a merger between Ciba-Gerigy and Sandoz in 1996.   It may also be recalled that Ciba-Geigy had a subsidiary in India, Hindustan Ciba-Geigy (HCG), which had applied to the government some 40 years ago to start a basic research division in this country to focus on digestive tract and amoebic and tropical diseases.

That made HCG one of the three companies in India that were engaged in basic research – the government owned National Chemical Laboratories (NCL), Amabalal Sarabhai Enterprises (ASE) and HCG.  ASE was the first to close down after the demise of the visionary founder of the group.  HCG, around 15 years ago, informed the government of its decision to shut shop. 

When interviewed on its decision to close the basic research centre, the HCG management confirmed the following:

(i) basic research is far too expensive and the returns from the pharma business in India too meagre.  Even though the division was started in India with the best of intentions, HCG believed that it did not warrant further continuation of this research facility.  The extensive land property at Goregaon, Mumbai, India, was subsequently sold at a very attractive price to a private developer (the Apte group).

<>(ii) the lack of IPR protection in India was not conducive to conducting research and developing new molecules in India; and
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<>(iii) All information of the molecules found in India had been sent to Ciba-Geigy's laboratories in Basel, Switzerland, for being used to discover new drugs.

Sceptics believe that HCG’s parent in Basel thus got all the information it could about tropical diseases and about the compounds that are used to curing them using traditional remedies (often prescribed by oriental schools of medicine like ayurveda and unani).  Any royalties that the company would get from patents would accrue only to the parent, and not to the Indian venture.  Sadly, the government of India has still not formulated a policy on such practices.  And these sceptics believe that, notwithstanding the claims of Ciba-Geigy’s new avataar Novartis, this story will now be repeated in India’s northern neighbour.

Obviously, what happens next in China will be watched very keenly by all in the pharmaceutical business.



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